Could TYSABRI Be Right for You?

If you have relapsing MS, ask yourself the following questions.

• Am I having relapses more often?
• Are my relapses more severe than before?
• Is it hard to recover from each relapse?
• Do my MRI results show activity each time I'm tested?
• Do I find that my physical disability is worsening over time?

If you answered yes to some or all of these questions, it may be time to talk to your doctor about TYSABRI.

TYSABRI is a prescription medicine approved for adults with relapsing forms of multiple sclerosis (MS) to slow the worsening of disability that is common in people with MS and decrease the number of flare-ups (relapses). But with benefits, TYSABRI also has risks.

Because TYSABRI increases the risk of progressive multifocal leukoencephalopathy (PML), a brain infection that usually causes death or severe disability, it is generally recommended for people who have not been helped enough by, or cannot tolerate, another treatment for MS. TYSABRI does not cure MS and has not been studied for longer than 2 years or in patients with chronic progressive MS.

Do not take TYSABRI if:

• You have PML
• You are allergic to TYSABRI

TYSABRI is not recommended if:

• You have a medical condition that can weaken your immune system — such as HIV infection or AIDS , leukemia or lymphoma — or if you've had an organ transplant.
• You are taking medicines that can weaken your immune system. Talk with your doctor about all of the medicines you take or have taken.